SFTPD anticorps (AA 241-336)

N° du produit ABIN7126935

Cet anticorps Souris Monoclonal détecte spécifiquement SFTPD dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour SFTPD anticorps (AA 241-336) (ABIN7126935)

Antigène: SFTPD (Surfactant Protein D (SFTPD))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SFTPD est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-SFTPD anticorps

Épitope: AA 241-336

Specificité: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa241-336) of human SFTPD protein (exact sequence is proprietary)

Isotype: IgG2

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Epithelial cells of the lung, skin, small intestine or bladder.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SFTPD

Antigène: SFTPD (Surfactant Protein D (SFTPD))

Autre désignation: SFTPD

Sujet: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D Surfactant protein D, PSPD, Pulmonary surfactant associated protein PSP-D, SFTP 4, SFTP4, SFTPD, SP-D, Surfactant associated protein pulmonary 4,Pulmonary Surfactant-Associated Protein D (SFTPD)
Cellular localisation: Secreted.

Poids moléculaire: 43kDa

ID gène: 6441, 253495

UniProt: P35247